Choline uptake inhibited by:	hemicholinium
Prevent ACh release, used in blepharospasm, strabismus, hyperhidrosis, dystonia and cosmetics.	Botulinum toxin
Reversibe AChE inhibitors	edrophonium physostigmine neostigmine
Irreversible AChE inhibitors	malathion parathion
Activation of M3 in sphincter of eye leads to	contraction-miosis
Clinical uses of Bethanecol	Rx-ileus, urinary retention.
Clinical uses of Methacoline	Dx-blonchial hyperreactivity
Clinical uses of Pilocarpine	Rx-Xerostomia, glaucoma.
Clinical uses of Edrophonium	Dx-Myasthenia gravis
Clinical uses of physostigmine	Rx-glaucoma, antidote in atropine overdose.
Clinical uses of Donezepil or Rivastigmine	Rx-Alzheimer disease
Clinical uses of atropine	Antispasmodic, antisecretory, AChE OD, antidiarrheal, ophtalmology (but long action).
Clinical uses of Ipratropium, tiotropium	Asthma and COPD
Clinical uses of Benzotropine	Parkinsonism and in acute extrapyramidal symptoms induced by antipsychotics. Lipid soluble (CNS entry)

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